The best way to set up an alert for a specific topic you are interested in is on Medline. Carry out your search on Medline as normal and then when logged into My Account save your search but select Auto-alert instead of permanent. It's a great way of keeping up to date with an area you are interested in or researching without you having to keep checking for new literature.
NICE provide a range of newsletters and alerts for you to sign up to, such as
To subscribe to any of these please see the link below.