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HSC Medicine, Dentistry and Healthcare Sciences Current Awareness Bulletins: Big 4 Journals

Big 4 Journals current awareness bulletin

Frequency: weekly

Links to articles in the current and previous 2 issues of this bulletin are displayed below.

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This bulletin is based on the equivalent bulletin produced by Bodleian Health Care Libraries:

9th June 2025

The BMJ: 9th June 2025

Balancing empathy and information in cancer treatment

Early onset colorectal cancer

How could regulation of NHS managers work—and will it happen?

How will robots help US surgeons?

Oral contraceptives with progestogens desogestrel or levonorgestrel and risk of intracranial meningioma

Sexual assault referral centres provide high quality support

Training bottlenecks and unemployment—bad for doctors, patients, and the public purse

Understanding the influence of abortion on 2024 US elections

“We can’t just admire the problem”: racism in medical research

JAMA: 12th June 2025

CONSORT 2025 statement: updated guideline for reporting randomized trials

Immunogenicity and safety of influenza and COVID-19 multicomponent vaccine in adults ≥50 years

Intravenous ferric carboxymaltose in heart failure with iron deficiency (FAIR-HF2 DZHK05)

Screening for syphilis infection during pregnancy: US Preventive Services Task Force reaffirmation recommendation statement

Trends in mental health diagnoses among publicly insured children

The Lancet: 14th June 2025

Acute rheumatic fever (review)

Efficacy and safety of first-line maintenance therapy with lurbinectedin plus atezolizumab in extensive-stage small-cell lung cancer (Imforte)

Retifanlimab with carboplatin and paclitaxel for locally recurrent or metastatic squamous cell carcinoma of the anal canal (POD1UM-303/InterAACT-2)

Surgery versus corticosteroid injection for carpal tunnel syndrome (DISTRICTS)

New England Journal of Medicine: 12th June 2025

Malnutrition in older adults

Nerandomilast in patients with idiopathic pulmonary fibrosis

Nerandomilast in patients with progressive pulmonary fibrosis

Once-weekly mazdutide in Chinese adults with obesity or overweight

Patient-specific in vivo gene editing to treat a rare genetic disease

Sustained clinical benefit of AAV gene therapy in severe hemophilia B

2nd June 2025

The BMJ: 26th May/2nd June 2025

Advances in the management of hepatitis B

Core GRADE 6: presenting the evidence in summary of findings tables

Core GRADE 7: principles for moving from evidence to recommendations and decisions

Current management of hypertrophic cardiomyopathy

Drug treatments for mild or moderate COVID-19: systematic review and network meta-analysis

Effect of dapagliflozin on metabolic dysfunction-associated steatohepatitis

Hospital league tables, targets, and performance incentives should be used with care

Need for planetary health perspective in guidance for complex interventions for climate and health

P2Y12 inhibitor or aspirin after percutaneous coronary intervention

Please explain the seriousness of the situation

Sacituzumab tirumotecan versus docetaxel for previously treated EGFR-mutated advanced non-small cell lung cancer

A village doctor-led mobile health intervention for cardiovascular risk reduction in rural China

Why US doctors are unionising

JAMA: 27th May/3rd June 2025

Iron deficiency in adults: a review

Long-term spending of accountable care organizations in the Medicare Shared Savings Program

Metformin for knee osteoarthritis in patients with overweight or obesity

Midurethral sling vs onabotulinumtoxinA in females with urinary incontinence

Prothrombin complex concentrate vs frozen plasma for coagulopathic bleeding in cardiac surgery (FARES-II)

Small cell lung cancer: a review

Use of life support and outcomes among patients admitted to intensive care units

Varenicline for youth nicotine vaping cessation

The Lancet: 31st May/7th June 2025

ACURATE neo2 valve versus commercially available transcatheter heart valves in patients with severe aortic stenosis (ACURATE IDE)

Antisense oligonucleotide jacifusen for FUS-ALS

A call to action: the second Lancet Commission on adolescent health and wellbeing

Claudin-18 isoform 2-specific CAR T-cell therapy (satri-cel) versus treatment of physician's choice for previously treated advanced gastric or gastro-oesophageal junction cancer (CT041-ST-01)

Comparison of supplemental breast cancer imaging techniques (BRAID)

Gastric cancer

Safety and efficacy of a novel ANGPTL4 inhibitory antibody for lipid lowering

Safety and efficacy of low-intensity versus standard monitoring following intravenous thrombolytic treatment in patients with acute ischaemic stroke (OPTIMISTmain)

New England Journal of Medicine: 29th May/5th June 2025

Debating race and the diagnosis of anemia — how medicine moved away from race-based standards

Cancer of unknown primary site

Franklin H. Epstein Lecture: the fetal-to-adult hemoglobin switch — mechanism and therapy

Loss of subsidized drug coverage and mortality among Medicare beneficiaries

Navigational bronchoscopy or transthoracic needle biopsy for lung nodules

Novel proteins to neutralize venom toxins

Omitting regional nodal irradiation after response to neoadjuvant chemotherapy

Oral semaglutide and cardiovascular outcomes in high-risk type 2 diabetes

Phase 3 trial of semaglutide in metabolic dysfunction–associated steatohepatitis

A phase 3 trial of upadacitinib for giant-cell arteritis

Setting for initial education about type 1 diabetes

Sotatercept in patients with pulmonary arterial hypertension at high risk for death

A trial of trimethoprim–sulfamethoxazole in pregnancy to improve birth outcomes

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