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HSC Medicine, Dentistry and Healthcare Sciences Current Awareness Bulletins: Big 4 Journals

Big 4 Journals current awareness bulletin

Frequency: weekly

Links to articles in the current and previous 2 issues of this bulletin are displayed below.

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This bulletin is based on the equivalent bulletin produced by Bodleian Health Care Libraries:

3rd March 2025

The BMJ: 3rd March 2025

Advances in the management of endometrial cancer

Assessment and management of common hand fractures in adults

The crumbling state of NHS buildings

Diagnosis and management of faecal incontinence in primary care

Hear my concerns and I will take your recommendations seriously

Physician associates and anaesthetic associates in UK

Projections for prevalence of Parkinson’s disease and its driving factors in 195 countries and territories to 2050: modelling study of Global Burden of Disease Study 2021

Trump 2.0 sends “a ripple of fear” through the reproductive health community fighting for safe abortions worldwide

JAMA: 4th March 2025

Electronic sepsis screening among patients admitted to hospital wards

Polygenic risk score added to conventional case finding to identify undiagnosed chronic obstructive pulmonary disease

Testicular germ cell tumors: a review

Transanal vs laparoscopic total mesorectal excision and 3-year disease-free survival in rectal cancer (TaLaR)

The Lancet: 8th March 2025

Global, regional, and national prevalence of adult overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021

Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021

Ivonescimab versus pembrolizumab for PD-L1-positive non-small cell lung cancer (HARMONi-2)

Tuberculosis (review)

New England Journal of Medicine: 6th March 2025

Male-partner treatment to prevent recurrence of bacterial vaginosis

Micronutrients — assessment, requirements, deficiencies, and interventions

Phase 1 study of AAV9.LAMP2B gene therapy in Danon disease

Remibrutinib in chronic spontaneous urticaria

Tirzepatide for obesity treatment and diabetes prevention

VITT-like monoclonal gammopathy of thrombotic significance

24th February 2025

The BMJ: 24th February 2025

Gaza’s health system is “completely eviscerated”—what happens now?

Glucagon-like peptide-1 receptor agonists and risk of suicidality among patients with type 2 diabetes

Plain versus drug balloon and stenting in severe ischaemia of the leg (BASIL-3)

The role of masks and respirators in preventing respiratory infections in healthcare and community settings

Screening for multiple cancers: evaluation must go beyond aggregate measures

What is medical Bluesky—and is it worth engaging with?

Who wants to leave WHO?

JAMA: 25th February 2025

2024 update of the RECOVER-adult Long COVID research index

Biomarker-guided antibiotic duration for hospitalized patients with suspected sepsis (ADAPT-Sepsis)

Camrelizumab vs placebo in combination with chemotherapy as neoadjuvant treatment in patients with early or locally advanced triple-negative breast cancer (CamRelief)

Essential thrombocythemia: a review

The Lancet: 1st March 2025

The African Critical Illness Outcomes Study (ACIOS): a point prevalence study of critical illness in 22 nations in Africa

Assessing the oncogenic risk: the long-term safety of autologous chimeric antigen receptor T cells

Extended treatment of venous thromboembolism with reduced-dose versus full-dose direct oral anticoagulants in patients at high risk of recurrence

A five-drug class model using routinely available clinical features to optimise prescribing in type 2 diabetes

Haemophilia (review)

New England Journal of Medicine: 27th February 2025

Blinatumomab in standard-risk B-cell acute lymphoblastic leukemia in children

Carceral health care

Choice of intravenous fluid for resuscitation in diabetic ketoacidosis

Embolization of the middle meningeal artery for chronic subdural hematoma

Highly pathogenic avian influenza A(H5N1) virus infections in humans

Oral infigratinib therapy in children with achondroplasia

17th February 2025

The BMJ: 17th February 2025

Common interventional procedures for chronic non-cancer spine pain: a systematic review and network meta-analysis of randomised trials

See also: Commonly used interventional procedures for non-cancer chronic spine pain: a clinical practice guideline

Discrepancies in neglected tropical diseases burden estimates in China: comparative study of real-world data and Global Burden of Disease 2021 data (2004-2020)

Training refugee and asylum seeking healthcare professionals: an ethical approach to UK workforce challenges

Why advocates for Parkinson’s disease prevention are cheering a US ban on a dry cleaning solvent

Why are black women still more likely to die in childbirth?

JAMA: 18th February 2025

Antiretroviral drugs for treatment and prevention of HIV in adults: 2024 recommendations of the International Antiviral Society–USA panel

Intra-arterial tenecteplase following endovascular reperfusion for large vessel occlusion acute ischemic stroke (POST-TNK)

Intra-arterial urokinase after endovascular reperfusion for acute ischemic stroke (POST-UK)

Palliative care initiated in the emergency department

The Lancet: 22nd February 2025

Endoscopic, ultrasound-guided, radiofrequency ablation of aldosterone-producing adenomas (FABULAS)

Exenatide once a week versus placebo as a potential disease-modifying treatment for people with Parkinson's disease in the UK

Gene therapy in children with AIPL1-associated severe retinal dystrophy: an open-label, first-in-human interventional study

Human schistosomiasis

New England Journal of Medicine: 20th February 2025

Catheter ablation or antiarrhythmic drugs for ventricular tachycardia

Fixed-duration acalabrutinib combinations in untreated chronic lymphocytic leukemia

Long-term effects of empagliflozin in patients with chronic kidney disease

Low-dose yellow fever vaccine in adults in Africa

Microvascular inflammation of kidney allografts and clinical outcomes

Tubal ectopic pregnancy

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