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HSC Medicine, Dentistry and Healthcare Sciences Current Awareness Bulletins: Big 4 Journals

Big 4 Journals current awareness bulletin

Frequency: weekly

Links to articles in the current and previous 2 issues of this bulletin are displayed below.

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This bulletin is based on the equivalent bulletin produced by Bodleian Health Care Libraries:

23rd June 2025

The BMJ: 23rd June 2025

Beyond body mass index: rethinking doctors’ advice for weight loss

Effect of UK Quality and Outcomes Framework pay-for-performance programme on quality of primary care: systematic review with quantitative synthesis

Living in a prison with no bars

Maternal and child nutrition: nutrition and weight management in pregnancy, and nutrition in children up to 5 years—summary of new NICE guidance

NHS inflexibility is behind falling vaccine uptake

Right C7 neurotomy at the intervertebral foramen plus intensive speech and language therapy versus intensive speech and language therapy alone for chronic post-stroke aphasia: multicentre, randomised controlled trial

JAMA: 26th June 2025

Extended caffeine for apnea in moderately preterm infants (MoCHA)

The microbiome and cancer: a translational science review

Modeling reemergence of vaccine-eliminated infectious diseases under declining vaccination in the US

A multidimensional diagnostic approach for chronic obstructive pulmonary disease

The Lancet: 28th June 2025

Community-based mentoring to reduce maternal and perinatal mortality in adolescent pregnancies in Sierra Leone (2YoungLives)

Early-onset type 2 diabetes: the next major diabetes transition

Managing early-onset type 2 diabetes in the individual and at the population level

Once-weekly insulin efsitora alfa versus once-daily insulin degludec in adults with type 2 diabetes currently treated with basal insulin (QWINT-3)

Once-weekly insulin efsitora alfa versus once-daily insulin glargine U100 in adults with type 2 diabetes treated with basal and prandial insulin (QWINT-4)

Understanding the drivers and consequences of early-onset type 2 diabetes

New England Journal of Medicine: 26th June 2025

AAV9-mediated gene therapy for infantile-onset Pompe’s disease

Efruxifermin in compensated liver cirrhosis caused by MASH

Encorafenib, cetuximab, and mFOLFOX6 in BRAF-mutated colorectal cancer

An evidence-based approach to Covid-19 vaccination

Generative AI in medicine — evaluating progress and challenges

Navigating the discontinuity crisis in medical education

Routine cerebral embolic protection during transcatheter aortic-valve implantation

16th June 2025

The BMJ: 16th June 2025

Are house calls making a comeback?

Comparative effectiveness of interventions to facilitate deprescription of benzodiazepines and other sedative hypnotics: systematic review and meta-analysis

Head injury in older people taking anticoagulants

Intermittent fasting strategies and their effects on body weight and other cardiometabolic risk factors: systematic review and network meta-analysis of randomised clinical trials

Ticagrelor doubts: inaccuracies uncovered in key studies for AstraZeneca’s billion dollar drug

JAMA: 17th June 2025

Antihypertensive medication timing and cardiovascular events and death: BedMed randomized clinical trial

Cataracts: a review

Herpes zoster vaccination and dementia occurrence

Spironolactone vs amiloride for resistant hypertension: a randomized clinical trial

The Lancet: 21st June 2025

Efficacy and safety of selumetinib in adults with neurofibromatosis type 1 and symptomatic, inoperable plexiform neurofibromas (KOMET)

Estimating the potential malaria morbidity and mortality avertable by the US President's Malaria Initiative in 2025: a geospatial modelling analysis

Moving the dial on diagnostics: an update from the Lancet Commission on diagnostics

Relacorilant and nab-paclitaxel in patients with platinum-resistant ovarian cancer (ROSELLA)

New England Journal of Medicine: 19th June 2025

Bevacizumab and erlotinib in hereditary and sporadic papillary kidney cancer

Corynebacterium diphtheriae outbreak in migrant populations in Europe

Nonoperative management of mismatch repair–deficient tumors

A phase 3 trial of inebilizumab in generalized myasthenia gravis

Unruptured intracranial aneurysms

Zongertinib in previously treated HER2-mutant non–small-cell lung cancer

9th June 2025

The BMJ: 9th June 2025

Balancing empathy and information in cancer treatment

Early onset colorectal cancer

How could regulation of NHS managers work—and will it happen?

How will robots help US surgeons?

Oral contraceptives with progestogens desogestrel or levonorgestrel and risk of intracranial meningioma

Sexual assault referral centres provide high quality support

Training bottlenecks and unemployment—bad for doctors, patients, and the public purse

Understanding the influence of abortion on 2024 US elections

“We can’t just admire the problem”: racism in medical research

JAMA: 12th June 2025

CONSORT 2025 statement: updated guideline for reporting randomized trials

Immunogenicity and safety of influenza and COVID-19 multicomponent vaccine in adults ≥50 years

Intravenous ferric carboxymaltose in heart failure with iron deficiency (FAIR-HF2 DZHK05)

Screening for syphilis infection during pregnancy: US Preventive Services Task Force reaffirmation recommendation statement

Trends in mental health diagnoses among publicly insured children

The Lancet: 14th June 2025

Acute rheumatic fever (review)

Efficacy and safety of first-line maintenance therapy with lurbinectedin plus atezolizumab in extensive-stage small-cell lung cancer (Imforte)

Retifanlimab with carboplatin and paclitaxel for locally recurrent or metastatic squamous cell carcinoma of the anal canal (POD1UM-303/InterAACT-2)

Surgery versus corticosteroid injection for carpal tunnel syndrome (DISTRICTS)

New England Journal of Medicine: 12th June 2025

Malnutrition in older adults

Nerandomilast in patients with idiopathic pulmonary fibrosis

Nerandomilast in patients with progressive pulmonary fibrosis

Once-weekly mazdutide in Chinese adults with obesity or overweight

Patient-specific in vivo gene editing to treat a rare genetic disease

Sustained clinical benefit of AAV gene therapy in severe hemophilia B

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