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HSC Medicine, Dentistry and Healthcare Sciences Current Awareness Bulletins: Diabetes and Endocrinology

Diabetes and Endocrinology current awareness bulletin

Frequency: Bi-monthly

Links to articles in the current and previous 2 issues of this bulletin are displayed below.

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September 2025

Associations of hysterectomy, oophorectomy, and hormone replacement therapy with the risk of type 2 diabetes mellitus in postmenopausal women

British Thyroid Association survey of Graves' disease management in the UK

Cognitive dysfunction in diabetes – the 'forgotten' diabetes complication: a narrative review

Comprehensive analysis of psychological, social and clinical aspects of polycystic ovary syndrome in pregnancy: insights from the Born in Bradford cohort study

Early-onset type 2 diabetes: the next major diabetes transition

The efficacy and safety of pembrolizumab in anaplastic thyroid carcinoma: a systematic review and meta-analysis

Genotype–phenotype correlation in germline TSH receptor activating mutation associated hyperthyroidism: a systematic review

Impact of diabetes mellitus on periapical, periodontal, and oral health and the potential confounders: a cross-sectional study

Is it possible to screen for primary aldosteronism effectively in primary care?

Management of maternal hypothyroidism in pregnancy: a Danish regional study

Managing early-onset type 2 diabetes in the individual and at the population level

Once-weekly insulin efsitora alfa versus once-daily insulin degludec in adults with type 2 diabetes currently treated with basal insulin (QWINT-3): a phase 3, randomised, non-inferiority trial

Once-weekly insulin efsitora alfa versus once-daily insulin glargine U100 in adults with type 2 diabetes treated with basal and prandial insulin (QWINT-4): a phase 3, randomised, non-inferiority trial

Re-evaluating the concept of remission in type 2 diabetes: a call for patient-centric approaches

The relationship between prediabetes and peripheral neuropathy—a systematic review and meta-analysis

The role of AMH and AMHR2 variants in polycystic ovary syndrome: a comprehensive analysis

Sex hormones and risk of incident dementia in men and postmenopausal women

Somapacitan for treating growth hormone deficiency in people 3 to 17 years (new NICE guideline TA1066)

Subacute thyroiditis as a post-COVID-19 complication: a systematic review

Thyroid diseases in patients with pituitary neuroendocrine tumours

Understanding the drivers and consequences of early-onset type 2 diabetes

Sources

BMC Infectious Diseases (Jul); Clinical Endocrinology (Aug-Sep); European Journal of Neurology (Jul); Journal of Dentistry (Aug); Lancet, The (Jun); Lancet Diabetes and Endocrinology, The (Jul); Scandinavian Journal of Primary Health Care (Jun); NICE website (Jun-Jul)

July 2025

Approach to the management of gastrointestinal manifestations in patients with phaeochromocytoma and paraganglioma

Association between maternal diabetes and neurodevelopmental outcomes in children: a systematic review and meta-analysis of 202 observational studies comprising 56.1 million pregnancies

Bidirectional relationship between diabetes and frailty in middle-aged and older adults: a systematic review and meta-analysis

Endothelial dysfunction in patients with type 2 diabetes: the truth is in the blood

Futility of plasmapheresis, insulin in normoglycaemic individuals, or heparin in the treatment of hypertriglyceridaemia-induced acute pancreatitis

Global Burden of type 2 diabetes in non-elderly individuals 1990 to 2021 and projections for 2050: a systematic analysis of the 2021 Global Burden of Disease Study

Glucose management indicator: do we need device-specific equations?

Impact of SGLT-2i on COPD exacerbations in patients with type 2 diabetes mellitus

Increased fatty acid-binding protein 4 levels are associated with the risk of developing retinopathy in type 2 diabetes mellitus patients

Long-term effects and effect heterogeneity of lifestyle and metformin interventions on type 2 diabetes incidence over 21 years in the US Diabetes Prevention Program randomised clinical trial

A novel diagnostic score for diagnosing arginine vasopressin deficiency (central diabetes insipidus) or primary polydipsia with basal laboratory and clinical parameters

Predictors of mortality in patients with multiple endocrine neoplasia type 1

A randomized controlled trial comparing testosterone enanthate and testosterone undecanoate as a gender affirming hormonal therapy in trans males

Redifferentiation therapy in unresectable or metastatic radioactive iodine refractory thyroid cancer: an International Thyroid Oncology Group statement

Setting for initial education about type 1 diabetes

Shared decisionmaking in the treatment of hypothyroidism

Tirzepatide and muscle composition changes in people with type 2 diabetes (SURPASS-3 MRI): a post-hoc analysis of a randomised, open-label, parallel-group, phase 3 trial

Tools to predict unilateral primary aldosteronism and optimise patient selection for adrenal vein sampling

Sources

Archives of Gerontology and Geriatrics (Aug); Clinical Endocrinology (Jul); Diabetes & Metabolism (Jul); Journal of Clinical Investigation, The (May); Lancet Diabetes and Endocrinology, The (Jun); NEJM (Jun)

May 2025

Adrenocortical carcinoma: a practical guide for clinicians

Age and sex differences in efficacy of treatments for type 2 diabetes: a network meta-analysis

Automated insulin delivery during the first 6 months postpartum (AiDAPT): a prespecified extension study

Challenges in care provision for children and adolescents with differences of sex development

The cost of adrenal insufficiency in England—analysis of NHS HES data

Definition and diagnostic criteria of clinical obesity

Diabetes can impact cellular immunity in solid tumors

Estimating direct tissue effects versus weight loss effects of incretin-based drugs for obesity on various chronic conditions

A five-drug class model using routinely available clinical features to optimise prescribing in type 2 diabetes: a prediction model development and validation study

Ghrelin: an emerging therapy for heart failure

Glucose-lowering medications and risk of chronic obstructive pulmonary disease exacerbations in patients with type 2 diabetes

Klinefelter syndrome: a review

The metabolic programming of pubertal onset

Polycystic ovary syndrome in the context of pituitary adenomas: prevalence, pathophysiology and clinical management

A randomized trial of automated insulin delivery in type 2 diabetes

Realigning diabetes regimens in older adults: a 4S Pathway to guide simplification and deprescribing strategies

The role of the hypothalamic–pituitary–thyroid axis in thyroid cancer

Sex hormones, sex hormone-binding globulin and sleep problems in females with polycystic ovary syndrome: a systematic review and meta-analysis

Systematic review and meta-analysis on the prevalence of radiotherapy-induced hypopituitarism in adults with primary non-pituitary brain tumours

Sources

Clinical Endocrinology (Apr-Jun); JAMA (Mar); JAMA Internal Medicine (Apr); Lancet, The (Mar); Lancet Diabetes and Endocrinology, The (Mar-May); NEJM (May); Trends in Immunology (Apr)

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