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HSC Medicine, Dentistry and Healthcare Sciences Current Awareness Bulletins: Diabetes and Endocrinology

Diabetes and Endocrinology current awareness bulletin

Frequency: Bi-monthly

Links to articles in the current and previous 2 issues of this bulletin are displayed below.

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November 2025

Adrenal insufficiency in adults: a review (JAMA)

Atypical diabetic neuropathies (BMJ)

Cardiovascular, kidney related, and weight loss effects of therapeutics for type 2 diabetes: a living clinical practice guideline

The central role of recovery of β-cell function in the remission of prediabetes: a prospective cohort study in Canada

Diagnosis and treatment of type 2 diabetes in adults: a review (JAMA)

Efficacy and safety of tirzepatide in children and adolescents with type 2 diabetes (SURPASS-PEDS): a randomised, double-blind, placebo-controlled, phase 3 trial

Exploring the role of GLP-1 agents in managing diabetic foot ulcers: a narrative and systematic review

Extending the duration of endocrine treatment for early breast cancer: patient-level meta-analysis of 12 randomised trials of aromatase inhibitors in 22 031 postmenopausal women already treated with at least 5 years of endocrine therapy

Facilitators of and barriers to deprescribing diabetes medications in older adults: a qualitative study

Food insecurity and the risk of diabetes: understanding the role of BMI as a mediator and moderator

The future of type 1 diabetes therapy

Global, regional, and national cascades of diabetes care, 2000–23: a systematic review and modelling analysis using findings from the Global Burden of Disease Study

Medications for adults with type 2 diabetes: a living systematic review and network meta-analysis

Minimum effective low dose of antithymocyte globulin in people aged 5–25 years with recent-onset stage 3 type 1 diabetes (MELD-ATG)

Nanotechnology based topical insulin delivery system: promising role in diabetic wound healing

Orforglipron, an oral small-molecule GLP-1 receptor agonist, in early type 2 diabetes

Palliative management of type 2 diabetes mellitus in patients with advanced cancer

Prolactin-secreting adenomas: pathogenesis, diagnosis, and management

Replacement of beta cells for type 1 diabetes

Stem cell–derived, fully differentiated islets for type 1 diabetes

Testosterone treatment in middle-aged and older men with hypogonadism

Tirzepatide for treating type 2 diabetes

Total and specific potato intake and risk of type 2 diabetes

Type 2 diabetes in South Asians

Sources

Australian Journal of General Practice (Aug); BMJ (Aug-Oct); JAMA (Aug-Sep); Journal of the American Geriatrics Society (Aug); Lancet (Aug-Oct); Lancet Diabetes and Endocrinology (Sep-Oct); NEJM (Aug-Sep); NICE website (Sep-Oct); Obesity (Jul); Wound Repair and Regeneration (Sep/Oct)

September 2025

Associations of hysterectomy, oophorectomy, and hormone replacement therapy with the risk of type 2 diabetes mellitus in postmenopausal women

British Thyroid Association survey of Graves' disease management in the UK

Cognitive dysfunction in diabetes – the 'forgotten' diabetes complication: a narrative review

Comprehensive analysis of psychological, social and clinical aspects of polycystic ovary syndrome in pregnancy: insights from the Born in Bradford cohort study

Early-onset type 2 diabetes: the next major diabetes transition

The efficacy and safety of pembrolizumab in anaplastic thyroid carcinoma: a systematic review and meta-analysis

Genotype–phenotype correlation in germline TSH receptor activating mutation associated hyperthyroidism: a systematic review

Impact of diabetes mellitus on periapical, periodontal, and oral health and the potential confounders: a cross-sectional study

Is it possible to screen for primary aldosteronism effectively in primary care?

Management of maternal hypothyroidism in pregnancy: a Danish regional study

Managing early-onset type 2 diabetes in the individual and at the population level

Once-weekly insulin efsitora alfa versus once-daily insulin degludec in adults with type 2 diabetes currently treated with basal insulin (QWINT-3): a phase 3, randomised, non-inferiority trial

Once-weekly insulin efsitora alfa versus once-daily insulin glargine U100 in adults with type 2 diabetes treated with basal and prandial insulin (QWINT-4): a phase 3, randomised, non-inferiority trial

Re-evaluating the concept of remission in type 2 diabetes: a call for patient-centric approaches

The relationship between prediabetes and peripheral neuropathy—a systematic review and meta-analysis

The role of AMH and AMHR2 variants in polycystic ovary syndrome: a comprehensive analysis

Sex hormones and risk of incident dementia in men and postmenopausal women

Somapacitan for treating growth hormone deficiency in people 3 to 17 years (new NICE guideline TA1066)

Subacute thyroiditis as a post-COVID-19 complication: a systematic review

Thyroid diseases in patients with pituitary neuroendocrine tumours

Understanding the drivers and consequences of early-onset type 2 diabetes

Sources

BMC Infectious Diseases (Jul); Clinical Endocrinology (Aug-Sep); European Journal of Neurology (Jul); Journal of Dentistry (Aug); Lancet, The (Jun); Lancet Diabetes and Endocrinology, The (Jul); Scandinavian Journal of Primary Health Care (Jun); NICE website (Jun-Jul)

July 2025

Approach to the management of gastrointestinal manifestations in patients with phaeochromocytoma and paraganglioma

Association between maternal diabetes and neurodevelopmental outcomes in children: a systematic review and meta-analysis of 202 observational studies comprising 56.1 million pregnancies

Bidirectional relationship between diabetes and frailty in middle-aged and older adults: a systematic review and meta-analysis

Endothelial dysfunction in patients with type 2 diabetes: the truth is in the blood

Futility of plasmapheresis, insulin in normoglycaemic individuals, or heparin in the treatment of hypertriglyceridaemia-induced acute pancreatitis

Global Burden of type 2 diabetes in non-elderly individuals 1990 to 2021 and projections for 2050: a systematic analysis of the 2021 Global Burden of Disease Study

Glucose management indicator: do we need device-specific equations?

Impact of SGLT-2i on COPD exacerbations in patients with type 2 diabetes mellitus

Increased fatty acid-binding protein 4 levels are associated with the risk of developing retinopathy in type 2 diabetes mellitus patients

Long-term effects and effect heterogeneity of lifestyle and metformin interventions on type 2 diabetes incidence over 21 years in the US Diabetes Prevention Program randomised clinical trial

A novel diagnostic score for diagnosing arginine vasopressin deficiency (central diabetes insipidus) or primary polydipsia with basal laboratory and clinical parameters

Predictors of mortality in patients with multiple endocrine neoplasia type 1

A randomized controlled trial comparing testosterone enanthate and testosterone undecanoate as a gender affirming hormonal therapy in trans males

Redifferentiation therapy in unresectable or metastatic radioactive iodine refractory thyroid cancer: an International Thyroid Oncology Group statement

Setting for initial education about type 1 diabetes

Shared decisionmaking in the treatment of hypothyroidism

Tirzepatide and muscle composition changes in people with type 2 diabetes (SURPASS-3 MRI): a post-hoc analysis of a randomised, open-label, parallel-group, phase 3 trial

Tools to predict unilateral primary aldosteronism and optimise patient selection for adrenal vein sampling

Sources

Archives of Gerontology and Geriatrics (Aug); Clinical Endocrinology (Jul); Diabetes & Metabolism (Jul); Journal of Clinical Investigation, The (May); Lancet Diabetes and Endocrinology, The (Jun); NEJM (Jun)

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