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HSC Medicine, Dentistry and Healthcare Sciences Current Awareness Bulletins: Diabetes and Endocrinology

Diabetes and Endocrinology current awareness bulletin

Frequency: Bi-monthly

Links to articles in the current and previous 2 issues of this bulletin are displayed below.

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May 2025

Adrenocortical carcinoma: a practical guide for clinicians

Age and sex differences in efficacy of treatments for type 2 diabetes: a network meta-analysis

Automated insulin delivery during the first 6 months postpartum (AiDAPT): a prespecified extension study

Challenges in care provision for children and adolescents with differences of sex development

The cost of adrenal insufficiency in England—analysis of NHS HES data

Definition and diagnostic criteria of clinical obesity

Diabetes can impact cellular immunity in solid tumors

Estimating direct tissue effects versus weight loss effects of incretin-based drugs for obesity on various chronic conditions

A five-drug class model using routinely available clinical features to optimise prescribing in type 2 diabetes: a prediction model development and validation study

Ghrelin: an emerging therapy for heart failure

Glucose-lowering medications and risk of chronic obstructive pulmonary disease exacerbations in patients with type 2 diabetes

Klinefelter syndrome: a review

The metabolic programming of pubertal onset

Polycystic ovary syndrome in the context of pituitary adenomas: prevalence, pathophysiology and clinical management

A randomized trial of automated insulin delivery in type 2 diabetes

Realigning diabetes regimens in older adults: a 4S Pathway to guide simplification and deprescribing strategies

The role of the hypothalamic–pituitary–thyroid axis in thyroid cancer

Sex hormones, sex hormone-binding globulin and sleep problems in females with polycystic ovary syndrome: a systematic review and meta-analysis

Systematic review and meta-analysis on the prevalence of radiotherapy-induced hypopituitarism in adults with primary non-pituitary brain tumours

Sources

Clinical Endocrinology (Apr-Jun); JAMA (Mar); JAMA Internal Medicine (Apr); Lancet, The (Mar); Lancet Diabetes and Endocrinology, The (Mar-May); NEJM (May); Trends in Immunology (Apr)

March 2025

Biomarkers and diagnostic thresholds for congenital hyperinsulinism

Dissection of type 2 diabetes: a genetic perspective  

Effect of antithyroid drugs treatment duration on the remission rates of Graves' disease in children and adolescents: a single-arm meta-analysis and systematic review

Effects of GLP-1 receptor agonists on kidney and cardiovascular disease outcomes   

Elacestrant for treating oestrogen receptor-positive HER2-negative advanced breast cancer with an ESR1 mutation after endocrine treatment (new NICE guideline TA1036)

Finerenone and new-onset diabetes in heart failure: a prespecified analysis of the FINEARTS-HF trial  

Glucagon‐like peptide 1 (GLP‐1) receptor agonists for people with chronic kidney disease and diabetes (new Cochrane intervention review)

Hybrid closed-loop insulin therapy and risk of severe hypoglycaemia and diabetic ketoacidosis in young people (aged 2–20 years) with type 1 diabetes: a population-based study  

Hypothalamic obesity: from basic mechanisms to clinical perspectives  

Is it time to revisit the recommendations for initiation of menopausal hormone therapy? 

Managing hypoglycaemia in patients with insulinoma

Metabolic dysfunction-associated steatotic liver disease: heterogeneous pathomechanisms and effectiveness of metabolism-based treatment  

New pituitary adenoma classification system to individualise management and improve long-term prognosis

Outcomes after medical treatment for primary aldosteronism  

Overweight and obesity among Israeli adolescents and the risk for serious morbidity in early young adulthood: a nationwide retrospective cohort study

PEG precipitation to detect macro-TSH in clinical practice: a systematic review

Prevalence of vitamin D deficiency with biochemical abnormalities in children undergoing vitamin D testing

Selpercatinib for advanced thyroid cancer with RET alterations after treatment with a targeted cancer drug in people 12 years and over (new NICE guideline TA1038)

Setmelanotide in patients aged 2–5 years with rare MC4R pathway-associated obesity (VENTURE)

Thyroidectomy without radioiodine in patients with low-risk thyroid cancer: 5 years of follow-up of the prospective randomised ESTIMABL2 trial  

Treatment regimens and glycaemic outcomes in more than 100 000 children with type 1 diabetes (2013–22): a longitudinal analysis of data from paediatric diabetes registries  

The use of prednisolone 2.5 mg daily during Ramadan fasting in patients with adrenal insufficiency

Sources

Clinical Endocrinology (Feb-Mar); Cochrane Library (Jan-Feb); Lancet Diabetes and Endocrinology, The (Jan-Feb); NICE website (Jan-Feb)

November 2024

Aberrant hormone receptors regulate a wide spectrum of endocrine tumors

Assessment of testicular function in boys and adolescents

Association of BMI, lipid-lowering medication, and age with prevalence of type 2 diabetes in adults with heterozygous familial hypercholesterolaemia: a worldwide cross-sectional study

Biomarkers in congenital adrenal hyperplasia

Biomarkers to inform the management of polycystic ovary syndrome: a review of systematic reviews

Cardiometabolic outcomes in offspring of women treated with metformin versus insulin for gestational diabetes: a systematic review and meta-analysis

Determinants of and barriers to diabetes care among patients with serious mental illness: a scoping review with recommendations

Developing oral chronotherapy for cortisol replacement in congenital adrenal hyperplasia

Effect of sodium–glucose co-transporter-2 inhibitors on survival free of organ support in patients hospitalised for COVID-19 (ACTIV-4a)

The effectiveness of delivery modalities of non-pharmacological diabetes prevention programs

Efficacy of using telecare services for community-dwelling people with diabetes: a systematic review and meta-analysis

Evolving epidemiological patterns of thyroid cancer and estimates of overdiagnosis in 2013–17 in 63 countries worldwide: a population-based study

Long-term health consequences of congenital adrenal hyperplasia

Male hypogonadism: pathogenesis, diagnosis, and management

The prevalence of gestational diabetes mellitus in polycystic ovary disease—a systematic review, meta-analysis, and exploration of associated risk factors

Preventing diabetes complications

SARS-CoV-2 infection and new-onset type 2 diabetes among pediatric patients, 2020-2022

Service evaluation suggests variation in clinical care provision in adults with congenital adrenal hyperplasia in the UK and Ireland

Sodium–glucose co-transporter-2 inhibitors for hospitalised patients with COVID-19

Working towards convergence of the clinical management of differences of sex development/intersex conditions and the human rights framework: a case study

Sources

Clinical Endocrinology (Oct-Nov); Diabetes and Metabolic Syndrome: Clinical Research and Reviews (Sep-Oct); Diabetology (Sep); Internal Medicine Journal (Aug); JAMA Network Open (Oct); Lancet Diabetes and Endocrinology, The (Oct-Nov); Primary Care Diabetes (Aug-Oct)

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