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HSC Medicine, Dentistry and Healthcare Sciences Current Awareness Bulletins: Diabetes and Endocrinology

Diabetes and Endocrinology current awareness bulletin

Frequency: Bi-monthly

Links to articles in the current and previous 2 issues of this bulletin are displayed below.

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July 2025

Approach to the management of gastrointestinal manifestations in patients with phaeochromocytoma and paraganglioma

Association between maternal diabetes and neurodevelopmental outcomes in children: a systematic review and meta-analysis of 202 observational studies comprising 56.1 million pregnancies

Bidirectional relationship between diabetes and frailty in middle-aged and older adults: a systematic review and meta-analysis

Endothelial dysfunction in patients with type 2 diabetes: the truth is in the blood

Futility of plasmapheresis, insulin in normoglycaemic individuals, or heparin in the treatment of hypertriglyceridaemia-induced acute pancreatitis

Global Burden of type 2 diabetes in non-elderly individuals 1990 to 2021 and projections for 2050: a systematic analysis of the 2021 Global Burden of Disease Study

Glucose management indicator: do we need device-specific equations?

Impact of SGLT-2i on COPD exacerbations in patients with type 2 diabetes mellitus

Increased fatty acid-binding protein 4 levels are associated with the risk of developing retinopathy in type 2 diabetes mellitus patients

Long-term effects and effect heterogeneity of lifestyle and metformin interventions on type 2 diabetes incidence over 21 years in the US Diabetes Prevention Program randomised clinical trial

A novel diagnostic score for diagnosing arginine vasopressin deficiency (central diabetes insipidus) or primary polydipsia with basal laboratory and clinical parameters

Predictors of mortality in patients with multiple endocrine neoplasia type 1

A randomized controlled trial comparing testosterone enanthate and testosterone undecanoate as a gender affirming hormonal therapy in trans males

Redifferentiation therapy in unresectable or metastatic radioactive iodine refractory thyroid cancer: an International Thyroid Oncology Group statement

Setting for initial education about type 1 diabetes

Shared decisionmaking in the treatment of hypothyroidism

Tirzepatide and muscle composition changes in people with type 2 diabetes (SURPASS-3 MRI): a post-hoc analysis of a randomised, open-label, parallel-group, phase 3 trial

Tools to predict unilateral primary aldosteronism and optimise patient selection for adrenal vein sampling

Sources

Archives of Gerontology and Geriatrics (Aug); Clinical Endocrinology (Jul); Diabetes & Metabolism (Jul); Journal of Clinical Investigation, The (May); Lancet Diabetes and Endocrinology, The (Jun); NEJM (Jun)

May 2025

Adrenocortical carcinoma: a practical guide for clinicians

Age and sex differences in efficacy of treatments for type 2 diabetes: a network meta-analysis

Automated insulin delivery during the first 6 months postpartum (AiDAPT): a prespecified extension study

Challenges in care provision for children and adolescents with differences of sex development

The cost of adrenal insufficiency in England—analysis of NHS HES data

Definition and diagnostic criteria of clinical obesity

Diabetes can impact cellular immunity in solid tumors

Estimating direct tissue effects versus weight loss effects of incretin-based drugs for obesity on various chronic conditions

A five-drug class model using routinely available clinical features to optimise prescribing in type 2 diabetes: a prediction model development and validation study

Ghrelin: an emerging therapy for heart failure

Glucose-lowering medications and risk of chronic obstructive pulmonary disease exacerbations in patients with type 2 diabetes

Klinefelter syndrome: a review

The metabolic programming of pubertal onset

Polycystic ovary syndrome in the context of pituitary adenomas: prevalence, pathophysiology and clinical management

A randomized trial of automated insulin delivery in type 2 diabetes

Realigning diabetes regimens in older adults: a 4S Pathway to guide simplification and deprescribing strategies

The role of the hypothalamic–pituitary–thyroid axis in thyroid cancer

Sex hormones, sex hormone-binding globulin and sleep problems in females with polycystic ovary syndrome: a systematic review and meta-analysis

Systematic review and meta-analysis on the prevalence of radiotherapy-induced hypopituitarism in adults with primary non-pituitary brain tumours

Sources

Clinical Endocrinology (Apr-Jun); JAMA (Mar); JAMA Internal Medicine (Apr); Lancet, The (Mar); Lancet Diabetes and Endocrinology, The (Mar-May); NEJM (May); Trends in Immunology (Apr)

March 2025

Biomarkers and diagnostic thresholds for congenital hyperinsulinism

Dissection of type 2 diabetes: a genetic perspective  

Effect of antithyroid drugs treatment duration on the remission rates of Graves' disease in children and adolescents: a single-arm meta-analysis and systematic review

Effects of GLP-1 receptor agonists on kidney and cardiovascular disease outcomes   

Elacestrant for treating oestrogen receptor-positive HER2-negative advanced breast cancer with an ESR1 mutation after endocrine treatment (new NICE guideline TA1036)

Finerenone and new-onset diabetes in heart failure: a prespecified analysis of the FINEARTS-HF trial  

Glucagon‐like peptide 1 (GLP‐1) receptor agonists for people with chronic kidney disease and diabetes (new Cochrane intervention review)

Hybrid closed-loop insulin therapy and risk of severe hypoglycaemia and diabetic ketoacidosis in young people (aged 2–20 years) with type 1 diabetes: a population-based study  

Hypothalamic obesity: from basic mechanisms to clinical perspectives  

Is it time to revisit the recommendations for initiation of menopausal hormone therapy? 

Managing hypoglycaemia in patients with insulinoma

Metabolic dysfunction-associated steatotic liver disease: heterogeneous pathomechanisms and effectiveness of metabolism-based treatment  

New pituitary adenoma classification system to individualise management and improve long-term prognosis

Outcomes after medical treatment for primary aldosteronism  

Overweight and obesity among Israeli adolescents and the risk for serious morbidity in early young adulthood: a nationwide retrospective cohort study

PEG precipitation to detect macro-TSH in clinical practice: a systematic review

Prevalence of vitamin D deficiency with biochemical abnormalities in children undergoing vitamin D testing

Selpercatinib for advanced thyroid cancer with RET alterations after treatment with a targeted cancer drug in people 12 years and over (new NICE guideline TA1038)

Setmelanotide in patients aged 2–5 years with rare MC4R pathway-associated obesity (VENTURE)

Thyroidectomy without radioiodine in patients with low-risk thyroid cancer: 5 years of follow-up of the prospective randomised ESTIMABL2 trial  

Treatment regimens and glycaemic outcomes in more than 100 000 children with type 1 diabetes (2013–22): a longitudinal analysis of data from paediatric diabetes registries  

The use of prednisolone 2.5 mg daily during Ramadan fasting in patients with adrenal insufficiency

Sources

Clinical Endocrinology (Feb-Mar); Cochrane Library (Jan-Feb); Lancet Diabetes and Endocrinology, The (Jan-Feb); NICE website (Jan-Feb)

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