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All content new unless marked as updated
Early versus late tracheostomy in people with multiple trauma
Exercise therapy for the treatment of delirium in the intensive care unit
First aid training for laypeople
Interventions for anal canal intraepithelial neoplasia (updated)
Interventions for preventing falls in older people in care facilities
Ketamine and other NMDA receptor antagonists for chronic pain
Natalizumab for multiple sclerosis
Non‐targeted immunosuppressive and immunomodulatory therapies for idiopathic inflammatory myopathies
Systemic pharmacological treatments for chronic plaque psoriasis: a network meta‐analysis (updated)
Telerehabilitation for neck pain
Vitamin D supplementation in pregnant or breastfeeding women or young children for preventing asthma
Bed frames for adults in acute medical or surgical hospital wards: late-stage assessment (HTE33)
Compression products for treating venous leg ulcers: late-stage assessment (HTE32)
Durvalumab with tremelimumab for untreated advanced or unresectable hepatocellular carcinoma (TA1090)
Guselkumab for previously treated moderately to severely active Crohn's disease (TA1095)
Guselkumab for treating moderately to severely active ulcerative colitis (TA1094)
Overweight and obesity management (QS212)
Ruxolitinib cream for treating non-segmental vitiligo in people 12 years and over (TA1088)
Single-step scaffold insertion for repairing symptomatic chondral knee defects (IPG793 – updated)
Tarlatamab for extensive-stage small-cell lung cancer after 2 or more treatments (TA1091)
Abortion care guideline (updated - 2nd edition)
Cochrane Library (Aug); NICE website (Aug); WHO website (Aug)
All content new, unless marked as ‘updated’
Continuous positive airway pressure versus methylxanthine for apnoea in preterm infants (updated)
Corticosteroids for treatment of leptospirosis
Desmopressin for nocturnal enuresis in children (updated)
Fertility‐sparing treatment for atypical endometrial hyperplasia and endometrial cancer
Interventions for improving adherence to amblyopia treatments in children
Low‐intensity shockwave therapy for erectile dysfunction
Midazolam for sedation of infants in the neonatal intensive care unit
Organised trauma systems and designated trauma centres for improving outcomes in injured patients
Palivizumab for preventing severe respiratory syncytial virus (RSV) infection in children (updated)
Perioperative interventions in pelvic organ prolapse surgery (updated)
Postextubation use of non‐invasive respiratory support in preterm infants: a network meta‐analysis
Rituximab for myasthenia gravis
Surgery for spontaneous supratentorial intracerebral haemorrhage
Surgical versus medical methods for second‐trimester induced abortion (updated)
Targeted immunosuppressive and immunomodulatory therapies for idiopathic inflammatory myopathies
Topical antibiotics for treating bacterial keratitis: a network meta‐analysis
Transcranial laser therapy for acute ischaemic stroke
Tumor necrosis factor‐alpha antagonists for treatment of pediatric Crohn’s disease
Vaginal lasers for treating stress urinary incontinence in women
Cardiovascular risk assessment and lipid modification (QS100 – updated)
Cenobamate for treating focal onset seizures in epilepsy (TA753 – updated)
Dapagliflozin for treating chronic kidney disease (TA1075)
Fruquintinib for previously treated metastatic colorectal cancer (TA1079)
Mirikizumab for previously treated moderately to severely active Crohn's disease (TA1080)
Nemolizumab for treating moderate to severe atopic dermatitis in people 12 years and over (TA1077)
One-piece closed bags for colostomies: late-stage assessment (HTE29)
Pulsed-field ablation for atrial fibrillation (IPG806)
Zanubrutinib for treating relapsed or refractory mantle cell lymphoma (TA1081)
Guidelines for the management of asymptomatic sexually transmitted infections
Cochrane Library (Jul); NICE website (Jul); WHO website (Jul)
All content new unless specified as updated
Antibiotics versus topical antiseptics for chronic suppurative otitis media (updated)
Antiplatelet versus anticoagulation treatment for people with heart failure in sinus rhythm (updated)
Aural toilet (ear cleaning) for chronic suppurative otitis media (updated)
Controlled ovarian stimulation protocols for assisted reproduction: a network meta‐analysis
Corticosteroids for treating sepsis in children and adults (updated)
Cycle regimens for endometrial preparation prior to frozen embryo transfer (updated)
Gonadotropin‐releasing hormone (GnRH) analogues for premenstrual syndrome (PMS)
Hormonal contraception for women at risk of HIV infection
Interventions for central serous chorioretinopathy: a network meta‐analysis (updated)
Interventions for fertility preservation in women with cancer undergoing chemotherapy
Interventions to prevent obesity in children aged 2 to 4 years old
Low‐complexity manual nucleic acid amplification tests for pulmonary tuberculosis in children
Lymphadenectomy or sentinel node biopsy for the management of endometrial cancer
Multifaceted behavioral interventions to improve topical glaucoma therapy adherence in adults
Non‐invasive respiratory support in preterm infants as primary mode: a network meta‐analysis
Postextubation use of non‐invasive respiratory support in preterm infants: a network meta‐analysis
Probiotics in infants for prevention of allergic disease (updated)
Progestogen for preventing miscarriage in women with recurrent miscarriage of unclear etiology (updated)
Silymarin for adults with metabolic dysfunction‐associated steatotic liver disease
Surgical approaches for inserting hemiarthroplasty of the hip in people with hip fractures
Systemic antibiotics for chronic suppurative otitis media (updated)
Topical antibiotics for chronic suppurative otitis media (updated)
Topical antibiotics with steroids for chronic suppurative otitis media (updated)
Topical antiseptics for chronic suppurative otitis media (updated)
Topical versus systemic antibiotics for chronic suppurative otitis media (updated)
The use of telemedicine services for medical abortion
Virtual reality for stroke rehabilitation
Atezolizumab for adjuvant treatment of resected non-small-cell lung cancer (TA1071)
Caesarean birth (NG192 – updated)
Efgartigimod for treating antibody-positive generalised myasthenia gravis (TA1069)
Headaches in over 12s: diagnosis and management (CG150 – updated)
Intrapartum care (NG235 – updated)
Laparoscopic insertion of an inactive implant for gastro-oesophageal reflux disease (IPG803)
Linzagolix for treating symptoms of endometriosis (TA1067)
Somapacitan for treating growth hormone deficiency in people 3 to 17 years (TA1066)
Sparsentan for treating primary IgA nephropathy (TA1074)
Spesolimab for treating generalised pustular psoriasis flares (TA1070)
Targeted muscle reinnervation for managing limb amputation pain (IPG804)
Topical antimicrobial dressings for locally infected leg ulcers: late-stage assessment (HTE27)
Transcatheter aortic valve implantation (TAVI) for native aortic valve regurgitation (IPG805)
Clinical management and infection prevention and control for mpox: living guideline, May 2025 (updated)
WHO consolidated guidelines on tuberculosis: module 3: diagnosis
WHO consolidated guidelines on tuberculosis: module 4: treatment and care
WHO guidelines for the treatment of patients with cystic echinococcosis
WHO guidelines on meningitis diagnosis, treatment and care
Cochrane Library (Jun); NICE website (Jun); WHO website (Apr-Jun)
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