HSC Medicine, Dentistry and Healthcare Sciences Current Awareness Bulletins: Guidelines and Cochrane Reviews

Guidelines and Cochrane Reviews

Frequency: Monthly

Links to articles in the current and previous 2 issues of this bulletin are displayed below.

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March 2025

All content new unless marked as updated

Cochrane reviews

Acupuncture for neonatal abstinence syndrome in newborn infants

Angioplasty or stenting for deep venous thrombosis

Antidepressants versus placebo for generalised anxiety disorder (GAD)

Azathioprine and 6‐mercaptopurine for maintenance of remission in ulcerative colitis (updated)

Balloon dilatation of the Eustachian tube for obstructive Eustachian tube dysfunction in adults

Breastfeeding interventions for preventing postpartum depression

Carbon dioxide detection for diagnosis of inadvertent respiratory tract placement of enterogastric tubes in children

Cardiovascular training for fatigue in people with cancer

Colchicine for the primary prevention of cardiovascular events

Diuretics for preventing and treating acute kidney injury

Electronic cigarettes for smoking cessation (updated)

Glucagon‐like peptide 1 (GLP‐1) receptor agonists for people with chronic kidney disease and diabetes

Home‐based educational interventions for children with asthma (updated)

Implementation strategies for WHO guidelines to prevent, detect, and treat postpartum hemorrhage

In vitro maturation in subfertile women with polycystic ovarian syndrome undergoing assisted reproduction (updated)

Influenza vaccination for healthcare workers who care for people aged 60 or older living in long‐term care institutions (updated)

Interventions for myopia control in children: a living systematic review and network meta‐analysis (updated)

Interventions to reduce non‐prescription antimicrobial sales in community pharmacies

Neoadjuvant chemotherapy before surgery versus surgery followed by chemotherapy for initial treatment in advanced epithelial ovarian cancer (updated)

Non‐vitamin K antagonist oral anticoagulants (NOACs) after transcatheter aortic valve replacement (TAVR): a network meta‐analysis

Physical rehabilitation approaches for the recovery of function and mobility following stroke (updated)

Precision nutrition‐based interventions for the management of obesity in children and adolescents up to the age of 19 years

Prophylactic transarterial embolization in patients with bleeding peptic ulcers following endoscopic control of bleeding

Renin inhibitors versus angiotensin receptor blockers for primary hypertension

Self‐management interventions for quality of life in adults with visual impairment

Transfusion of blood and blood products for the management of postpartum haemorrhage

Tumor necrosis factor (TNF) inhibitors for juvenile idiopathic arthritis

Tumor necrosis factor (TNF) inhibitors for psoriatic arthritis

NICE guidelines

Advanced breast cancer: diagnosis and treatment (CG81 – updated)

Artificial intelligence-derived software to analyse chest X-rays for suspected lung cancer in primary care referrals: early value assessment (HTE12 – updated)

Digital technologies to support self-management of COPD: early value assessment (HTE19 – updated)

Durvalumab with etoposide and either carboplatin or cisplatin for untreated extensive-stage small-cell lung cancer

Early and locally advanced breast cancer: diagnosis and management (NG101 – updated)

Elacestrant for treating oestrogen receptor-positive HER2-negative advanced breast cancer with an ESR1 mutation after endocrine treatment (TA1036)

Exagamglogene autotemcel for treating severe sickle cell disease in people 12 years and over (TA1044)

Ganaxolone for treating seizures caused by CDKL5 deficiency disorder in people 2 years and over (TA1033)

Intravascular lithotripsy to treat calcified coronary arteries during percutaneous coronary intervention (IPG802)

Olaparib for treating BRCA mutation-positive HER2-negative advanced breast cancer after chemotherapy (TA1040)

Osimertinib for adjuvant treatment of EGFR mutation-positive non-small-cell lung cancer after complete tumour resection (TA1043)

Ovarian cancer (QS18 – updated)

Pembrolizumab for adjuvant treatment of resected non-small-cell lung cancer (TA1037)

Selpercatinib for advanced thyroid cancer with RET alterations after treatment with a targeted cancer drug in people 12 years and over (TA1038)

Selpercatinib for advanced thyroid cancer with RET alterations untreated with a targeted cancer drug in people 12 years and over (TA 1039)

Selpercatinib for previously treated RET fusion-positive advanced non-small-cell lung cancer (TA1042)

Tobacco: preventing uptake, promoting quitting and treating dependence (NG209 - updated)

Sources

Cochrane Library (Feb); NICE website (Feb)

February 2025

All content new, unless marked as ‘updated’

Cochrane reviews

Alendronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women (updated)

Ankle‐foot orthoses for improving walking in adults with calf muscle weakness due to neuromuscular disorders

Antidepressants versus placebo for generalised anxiety disorder (GAD)

Anti‐PD‐1 and anti‐PD‐L1 antibodies for glioma

Caesarean myomectomy in pregnant women with uterine fibroids

Calorie (energy) labelling for changing selection and consumption of food or alcohol

Differences in the effectiveness of individual‐level smoking cessation interventions by socioeconomic status

Direct factor Xa inhibitors versus low molecular weight heparins or vitamin K antagonists for prevention of venous thromboembolism in elective primary hip or knee replacement or hip fracture repair

Diuretics for preventing and treating acute kidney injury

Electronic cigarettes for smoking cessation (updated)

Gonadotropin‐releasing hormone agonist protocols for pituitary suppression in assisted reproduction (updated)

Incentives for smoking cessation (updated)

Interrupted versus uninterrupted anticoagulation for cardiac rhythm management device insertion

Interventions for quitting vaping

Interventions implemented through sporting organisations for promoting healthy behaviour or improving health outcomes

Interventions to reduce non‐prescription antimicrobial sales in community pharmacies

Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis (updated)

Lurasidone versus typical antipsychotics for schizophrenia

Oral and intranasal aspirin desensitisation for non‐steroidal anti‐inflammatory drug (NSAID)‐exacerbated respiratory disease

Precision nutrition‐based interventions for the management of obesity in children and adolescents up to the age of 19 years

Preservation of the azygos vein versus ligation of the azygos vein during primary surgical repair of congenital esophageal atresia

Pre‐emptive treatment for cytomegalovirus viraemia to prevent cytomegalovirus disease in solid organ transplant recipients (updated)

Tests for diagnosis of postpartum haemorrhage at vaginal birth

Thrombolysis for aneurysmal subarachnoid haemorrhage

Tranexamic acid for preventing postpartum haemorrhage after vaginal birth (updated)

Virtual reality for multiple sclerosis rehabilitation

NICE guidelines

January 2025

All content new unless specified as updated

Cochrane reviews

Azathioprine for people with multiple sclerosis

Cell salvage for the management of postpartum haemorrhage

Chemotherapy and radiotherapy for advanced pancreatic cancer (updated)

Comparisons of approaches to pelvic floor muscle training for urinary incontinence in women (updated)

Cycled light in the intensive care unit for preterm and low birth weight infants (updated)

Diagnostic test accuracy of self‐administered cognitive assessment tools for dementia

Effect and safety of intravenous iron compared to oral iron for treatment of iron deficiency anaemia in pregnancy

The effect of sample site and collection procedure on identification of SARS‐CoV‐2 infection

Exercise therapy for chronic fatigue syndrome

Fluid restriction for treatment of symptomatic patent ductus arteriosus in preterm infants

Gender differences in the context of interventions for improving health literacy in migrants: a qualitative evidence synthesis

Higher blood pressure targets for hypertension in older adults

Non‐steroidal anti‐inflammatory drugs for treating symptomatic uncomplicated urinary tract infections in non‐pregnant adult women

Oocyte activation for women following intracytoplasmic sperm injection (ICSI)

Prevention of self‐harm and suicide in young people up to the age of 25 in education settings

Sex and gender as predictors for allograft and patient‐relevant outcomes after kidney transplantation

Standard‐ versus extended‐duration anticoagulation for primary venous thromboembolism prophylaxis in acutely ill medical patients

Strategies for enhancing the implementation of school‐based policies or practices targeting diet, physical activity, obesity, tobacco or alcohol use

Treatment for women with postpartum iron deficiency anaemia (updated)

Unintended consequences of measures implemented in the school setting to contain the COVID‐19 pandemic: a scoping review

NICE guidelines

Bevacizumab gamma for treating wet age-related macular degeneration (TA1022)

Crizotinib for treating ROS1-positive advanced non-small-cell lung cancer (TA1021)

Digital technologies to support self-management of COPD: early value assessment (HTE19)

Direct skeletal fixation of limb prostheses using an intraosseous transcutaneous implant (IPG795)

Elranatamab for treating relapsed and refractory multiple myeloma after 3 or more treatments (TA1023)

Home-testing devices for diagnosing obstructive sleep apnoea hypopnoea syndrome (DG62)

Meningitis (bacterial) and meningococcal disease (QS19 - updated)

MRI-guided focused ultrasound subthalamotomy for treating Parkinson's (IPG797)

MRI-guided focused ultrasound thalamotomy for treating moderate to severe tremor in Parkinson's (IPG796)

Tirzepatide for managing overweight and obesity (TA1026)

Ublituximab for treating relapsing multiple sclerosis (TA1025)

Urinary tract infection (recurrent): antimicrobial prescribing (NG112 – updated)

Sources

Cochrane Library (Dec); NICE website (Dec)

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