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HSC Medicine, Dentistry and Healthcare Sciences Current Awareness Bulletins: Cancer Medicine and Surgery

Cancer Medicine and Surgery current awareness bulletin

Frequency: Bi-monthly

Links to articles in the current and previous 2 issues of this bulletin are displayed below.

To receive email notifications about new issues of this bulletin, please email: richard.fallis@healthcarelibrary.qub.ac.uk

May 2025

Advances in the management of endometrial cancer

Assessment of a polygenic risk score in screening for prostate cancer

Blinatumomab with chemotherapy for consolidation treatment of Philadelphia-chromosome-negative CD19-positive minimal residual disease-negative B-cell precursor acute lymphoblastic leukaemia (new NICE guideline TA1049)

Fear of the cancer coming back: a metasynthesis of fear of recurrence in breast cancer

Global cancer burden attributable to excess body weight, 1990 to 2021, decomposed by population size, aging, and epidemiological change

Global, regional, and national burden of early-onset colorectal cancer and projection to 2050: an analysis based on the Global Burden of Disease Study 2021

Intra-tumoral bacteria in breast cancer and intervention strategies

Lisocabtagene maraleucel for treating relapsed or refractory large B-cell lymphoma after first-line chemoimmunotherapy when a stem cell transplant is suitable (new NICE guideline TA1048)

Lymphatic transport in anti-tumor immunity and metastasis

Multimodal interventions for cachexia management (new Cochrane intervention review)

Next‐generation sequencing for guiding matched targeted therapies in people with relapsed or metastatic cancer (new Cochrane intervention review)

Pancreatic cancer (Lancet review)

Patient and caregiver experience of diagnosis, treatment, and living with recurrent oropharyngeal cancer

Positron emission tomography‐adapted therapy for first‐line treatment in adults with Hodgkin lymphoma (new Cochrane intervention review)

Racial disparities in thyroid cancer outcomes: a systematic review

Testicular germ cell tumors: a review

Transanal vs laparoscopic total mesorectal excision and 3-year disease-free survival in rectal cancer: the TaLaR randomized clinical trial

Zolbetuximab with chemotherapy for untreated claudin-18.2-positive HER2-negative unresectable advanced gastric or gastro-oesophageal junction adenocarcinoma (new NICE guideline TA1046)

Sources

Advanced Drug Delivery Reviews (Feb); American Journal of Surgery (Feb); BMJ, The (Mar); Cochrane Library (Mar-Apr); JAMA (Mar); JAMA Otolaryngology - Head & Neck Surgery (Feb); Journal of Experimental Medicine (Feb); NEJM (Apr); NICE website (Mar); Obesity (Mar); Public Health (Jan); Public Health Nursing (Jan/Feb)

March 2025

Advanced breast cancer: diagnosis and treatment (updated NICE guideline CG81)

Anhydrous sodium thiosulfate for preventing hearing loss caused by cisplatin chemotherapy in people 1 month to 17 years with localised solid tumours (new NICE guideline TA1034)

Annual versus less frequent mammographic surveillance in people with breast cancer aged 50 years and older in the UK (Mammo-50): a multicentre, randomised, phase 3, non-inferiority trial

Artificial intelligence-derived software to analyse chest X-rays for suspected lung cancer in primary care referrals: early value assessment (updated NICE guideline HTE12)

Durvalumab with chemotherapy before surgery (neoadjuvant) then alone after surgery (adjuvant) for treating resectable non-small-cell lung cancer (new NICE guideline TA1030)

Durvalumab with etoposide and either carboplatin or cisplatin for untreated extensive-stage small-cell lung cancer (new NICE guideline TA1041)

Early and locally advanced breast cancer: diagnosis and management (updated NICE guideline NG101)

Elacestrant for treating oestrogen receptor-positive HER2-negative advanced breast cancer with an ESR1 mutation after endocrine treatment (new NICE guideline TA1036)

Home hospitalization in palliative care for advanced cancer and dementia: a systematic review

Imaging in diagnosis and active surveillance for prostate cancer: a review

Intratumoral administration of mRNA COVID-19 vaccine delays melanoma growth in mice

Neoadjuvant chemotherapy before surgery versus surgery followed by chemotherapy for initial treatment in advanced epithelial ovarian cancer (updated Cochrane intervention review)

Olaparib for treating BRCA mutation-positive HER2-negative advanced breast cancer after chemotherapy (new NICE guideline TA1040)

Ovarian cancer (updated NICE guideline QS18)

Pembrolizumab for adjuvant treatment of resected non-small-cell lung cancer (new NICE guideline TA1037)

Selpercatinib for advanced thyroid cancer with RET alterations after treatment with a targeted cancer drug in people 12 years and over (new NICE guideline TA1038)

Selpercatinib for advanced thyroid cancer with RET alterations untreated with a targeted cancer drug in people 12 years and over (new NICE guideline TA1039)

Selpercatinib for previously treated RET fusion-positive advanced non-small-cell lung cancer (new NICE guideline TA1042)

Tebentafusp for treating advanced uveal melanoma (new NICE guideline IPG798)

Sources

Cochrane Library (Jan-Feb); JAMA Surgery (Jan); Journal of Pain and Symptom Management (Mar); Lancet, The (Jan); NICE website (Jan-Feb); Scientific Reports (Feb)

January 2025

Advanced prostate cancer experimental radioactive treatment—clinical trial decision making: patient experiences

Cancer chemotherapy: incidence and predictors of 30-day mortality

Cancer pain self-management interventions in adults: scoping review

Cancer treatment refusal decisions in advanced cancer: a retrospective case–control study

CAR T cells and T-cell therapies for cancer: a translational science review

Colorectal cancer survivors’ quality of life: a qualitative study of unmet need

Decision tree algorithm to predict mortality in incurable cancer: a new prognostic model

Did Michelangelo paint a young adult woman with breast cancer in “The Flood” (Sistine Chapel, Rome)?

Digital health for cancer symptom management in palliative medicine: systematic review

The impact of intestinal and mammary microbiomes on breast cancer development: a review on the microbiota and oestrobolome roles in tumour microenvironments

Introducing palliative care in advanced cancer: a systematic review

Medical cannabis use in young adults with cancer: a self-reported survey study

Oesophageal cancer (Lancet seminar)

Opioid initiation timing and palliative care referrals in advanced cancer: retrospective study

The optimal timing of breast cancer surgery after COVID-19 infection: an observational study

Osimerinib haematological toxicities in non-small cell lung cancer: a randomised controlled trials meta-analysis

Paediatric relapsed acute leukaemia: curative intent chemotherapy improves quality of life

Pain management effectiveness in advanced cancer: palliative care unit inpatient study

Preoperative chemoradiotherapy for resectable gastric cancer

RNA-loaded nanoparticles for the treatment of hematological cancers

Thirty-day mortality in hospitalised patients with lung cancer: incidence and predictors

What is known about the role of clinical ethics services in cancer care? A systematic/narrative literature review

Sources

Advanced Drug Delivery Reviews (Nov); American Journal of Surgery, The (Nov); BMC Cancer (Nov); BMJ Supportive and Palliative Care (Nov-Dec); Breast, The (Dec); JAMA (Dec); Lancet, The (Nov); NEJM (Nov)

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