Skip to Main Content Skip to Main Content

HSC Medicine, Dentistry and Healthcare Sciences Current Awareness Bulletins: Blood

Blood current awareness bulletin

Frequency: Bi-monthly

Links to articles in the current and previous 2 issues of this bulletin are displayed below.

To receive email notifications about new issues of this bulletin, please email: richard.fallis@healthcarelibrary.qub.ac.uk

May 2025

Blinatumomab with chemotherapy for consolidation treatment of Philadelphia-chromosome-negative CD19-positive minimal residual disease-negative B-cell precursor acute lymphoblastic leukaemia (new NICE guideline TA1049)

Classification and risk stratification in T-lineage acute lymphoblastic leukemia

The contribution of the monocyte-macrophage lineage to immunotherapy outcomes

Don't break the (blood) bank: can waste be minimized in a whole blood program?

Essential thrombocythemia: a review

The evolution of treatment-free remission

FDA-approved therapies for chronic GVHD

Genetic subtypes of B-cell acute lymphoblastic leukemia in adults

Haemophilia (Lancet seminar)

Honing CAR T cells to tackle acute myeloid leukemia

How I diagnose and treat acute infection–associated purpura fulminans

How I manage patients with unexplained cytopenia

How I treat acute myeloid leukemia with differentiation therapy

How I treat patients with AML using azacitidine and venetoclax

How I treat quantitative fibrinogen disorders

How I treat secondary acute myeloid leukemia

How I use maintenance therapy in acute myeloid leukemia

Illustrated capsules from the Advanced Course in Platelet Research

Impact of new medications on the treatment of immune TTP

Incorporation of immunotherapy into frontline treatment for adults with B-cell precursor acute lymphoblastic leukemia

Long-term outcomes of tyrosine kinase inhibitors in chronic myeloid leukemia

Novel mechanisms of resistance in CLL: variant BTK mutations in second-generation and noncovalent BTK inhibitors

Novel treatment strategies for chronic myeloid leukemia

The present and future of CAR T-cell therapy for adult B-cell ALL

Red blood cell transfusion management for people undergoing cardiac surgery for congenital heart disease (new Cochrane intervention review)

The United Kingdom Infected Blood Inquiry: its findings and lessons for the future of transfusion

Sources

American Journal of Surgery (Feb); Blood (20th Feb - 10th Apr); Cochrane Library (Mar-Apr); JAMA (Feb); Lancet, The (Mar); NICE website (Mar); Research and Practice in Thrombosis and Haemostasis (Feb)

March 2025

Acute promyelocytic leukemia: long-term outcomes from the HARMONY project

Andexanet alfa for reversing anticoagulation from apixaban or rivaroxaban (updated NICE guideline TA697)

β-Thalassemia minor is associated with high rates of worsening anemia in pregnancy

Building the future management of follicular lymphoma with T-cell–redirecting strategies

Cost-effectiveness of iptacopan for paroxysmal nocturnal hemoglobinuria

The current landscape of frontline large B-cell lymphoma trials

Current myeloproliferative neoplasm scoring systems for clinical practice

Frontline management of mantle cell lymphoma

Genetic and clinical spectrum of SAMD9 and SAMD9L syndromes: from variant interpretation to patient management

Genetic iron overload aggravates, and pharmacological iron restriction improves, MDS pathophysiology in a preclinical study

High-risk MCL: recognition and treatment

How I treat/manage:

Management of iron overload: lessons from transfusion-dependent hemoglobinopathies

Menin inhibitors in the treatment of acute myeloid leukemia

Palliative care in hematology: a systematic review of the components, effectiveness, and implementation

Prothrombotic antibodies targeting the spike protein's receptor-binding domain in severe COVID-19

Transfusion of blood and blood products for the management of postpartum haemorrhage (new Cochrane intervention review)

Treatment of relapsed/refractory MCL

Unraveling MCL biology to understand resistance and identify vulnerabilities

Vadadustat for treating symptomatic anaemia in adults having dialysis for chronic kidney disease (new NICE guideline TA1035

Sources

Blood (Jan-13th Feb); Cochrane Library (Feb); Journal of Pain and Symptom Management (Jan); NICE website (Jan-Feb)

January 2025

Are we there yet? CAR-T therapy in multiple myeloma

Blood coagulation factor IX: structural insights impacting hemophilia B therapy

Cell salvage for the management of postpartum haemorrhage (new Cochrane review)

Central nervous system prophylaxis in large B-cell lymphoma: a British Society for Haematology Good Practice Paper

Chimeric antigen receptor T-cell therapy for haematological malignancies

Clinical features, pathophysiology, and management of acute myelopathy following CAR T-cell therapy

Coagulation factor VIII: biological basis of emerging hemophilia A therapies

Dialysis for chronic kidney failure: a review

DLBCL: who is high risk and how should treatment be optimized?

Effect and safety of intravenous iron compared to oral iron for treatment of iron deficiency anaemia in pregnancy (new Cochrane review)

Exploring the role of Large Language Models in haematology: a focused review of applications, benefits and limitations

            See also: The power and perils of large language models in haematology

Haemodiafiltration versus haemodialysis for kidney failure

The high-grade B-cell lymphomas: double hit and more

How unique structural adaptations support and coordinate the complex function of von Willebrand factor

Paediatric relapsed acute leukaemia: curative intent chemotherapy improves quality of life

Peripheral T-cell lymphoma: are all patients high risk?

Perspectives on drug development in chronic myelomonocytic leukemia: changing the paradigm

Platelet generation in vivo and in vitro

Primary large B-cell lymphomas of immune-privileged sites

RNA-loaded nanoparticles for the treatment of hematological cancers

Sequencing of therapy for patients with diffuse large B-cell lymphoma in the era of novel drugs

T-cell lymphomas in recipients of CAR-T cells: assessing risks and causalities

Therapeutic strategies targeting aberrant RNA splicing in myeloid malignancies

Treatment for women with postpartum iron deficiency anaemia (updated Cochrane review)

Understanding splenic B-cell lymphoma/leukaemia with prominent nucleoli: diagnosis, underpinnings for disease classification and future directions

Sources

Advanced Drug Delivery Reviews (Nov); Blood (Nov-Dec); BMJ Supportive and Palliative Care (Nov); British Journal of Haematology (Nov-Dec); Cochrane Library (Dec); JAMA (Nov); Lancet, The (Nov)

Disclaimer

The Healthcare Library cannot guarantee the correctness or completeness of the information in these bulletins. The information is subject to change and we cannot guarantee it will remain up-to-date. It is your responsibility to check the accuracy and validity of the information. These bulletins are the property of the Healthcare Library; please credit us if re-using or distributing content from them.