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HSC Medicine, Dentistry and Healthcare Sciences Current Awareness Bulletins: General Internal Medicine

General Internal Medicine current awareness bulletin

Frequency: Bi-monthly

Links to articles in the current and previous 2 issues of this bulletin are displayed below.

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June 2024

Atogepant for preventing migraine (new NICE guidance TA973)

Artificial intelligence (AI)-derived software to help clinical decision making in stroke (updated NICE guidance DG57)

Breakthrough advances enhancing care in ATTR amyloid cardiomyopathy 10.1016/j.ejim.2024.01.001 s

Calcium supplementation for people with overweight or obesity (new Cochrane intervention review) 10.1002/14651858.CD012268.pub2

Complication rates of central venous catheters: a systematic review and meta-analysis 10.1001/jamainternmed.2023.8232

Dementia prevention and treatment: a narrative review 10.1001/jamainternmed.2023.8522

Endometriosis: diagnosis and management (updated NICE guidance NG73)

Enduring echoes: post-infectious long-term changes in innate immunity 10.1016/j.ejim.2023.12.020

Focus on senescence: clinical significance and practical applications 10.1111/joim.13775  

Gout and its management 10.1111/imj.16382  

Guidance on energy and macronutrients across the life span 10.1056/NEJMra2214275

The increasing costs of medicines and their implications for patients, physicians and the health system 10.1111/imj.16370

Knowledge on cause, clinical manifestation and treatment for fibromyalgia among medical doctors: a worldwide survey 10.1111/papr.13339

Malignant ovarian and testicular germ cell tumors: common characteristics but different prognoses 10.1111/joim.13778  

Reducing hospitalizations and multidrug-resistant organisms via regional decolonization in hospitals and nursing homes 10.1001/jama.2024.2759

Metabolic dysfunction-associated steatotic liver disease (MASLD): dietary and pharmacological treatment 10.1016/j.ejim.2024.01.005; management of cardiovascular risk 10.1016/j.ejim.2023.11.012; natural history 10.1016/j.ejim.2023.11.005; non-invasive testing and risk-stratification 10.1016/j.ejim.2024.01.013

Precision medicine in cardiovascular therapeutics: evaluating the role of pharmacogenetic analysis prior to drug treatment 10.1111/joim.13772  

Reframing prediabetes: a call for better risk stratification and intervention 10.1111/joim.13786

Resistant hypertension: diagnosis, evaluation, and treatment practical approach 10.1016/j.ejim.2023.12.026

Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults (updated Cochrane intervention review) 10.1002/14651858.CD010136.pub4

Zinc for prevention and treatment of the common cold (new Cochrane intervention review) 10.1002/14651858.CD014914.pub2


Cochrane Library (Apr-May); European Journal of Internal Medicine (Apr-May); Internal Medicine Journal (Apr-May); JAMA (Apr); JAMA Internal Medicine (Apr-May); Journal of Internal Medicine (May-Jun); NEJM (10th Apr); NICE website (Apr-May); Pain Practice (Apr)

April 2024

Antibiotic prophylaxis for leptospirosis (new Cochrane review) 10.1002/14651858.CD014959.pub2

Antibiotics for treatment of leptospirosis (new Cochrane review) 10.1002/14651858.CD014960.pub2

Anticoagulation in atrial fibrillation. A large real-world update 10.1016/j.ejim.2023.10.010

Association of depression with myocardial infarction with non-obstructive coronary arteries 10.55729/2000-9666.1296

Clinical presentation, course, and prognosis of patients with mixed connective tissue disease 10.1111/joim.13752  

COVID-19 infection and clinical outcomes in hospitalized patients with rheumatoid arthritis: insights from the National Inpatient Sample 10.55729/2000-9666.1288

First trimester use of buprenorphine or methadone and the risk of congenital malformations 10.1001/jamainternmed.2023.6986

Lung cancer: diagnosis and management (updated NICE guideline NG122)

Meningitis (bacterial) and meningococcal disease: recognition, diagnosis and management (new NICE guideline NG240)

Neonatal infection: antibiotics for prevention and treatment (updated NICE guideline NG195)

Non‐clotting factor therapies for preventing bleeds in people with congenital hemophilia A or B (new Cochrane review) 10.1002/14651858.CD014544.pub2

Non-conventional immunomodulation in the management of sepsis 10.1016/j.ejim.2023.10.032

Nosocomial COVID-19 infection in the era of vaccination and antiviral therapy 10.1111/imj.16298

Ovarian cancer: identifying and managing familial and genetic risk (new NICE guideline NG241)

Prebiotics for induction and maintenance of remission in ulcerative colitis (new Cochrane review) 10.1002/14651858.CD015084.pub2

Prevalence and prognostic value of electrocardiographic abnormalities in hypokalemia 10.1111/joim.13757  

Risk factors for malignancy and serious infection in patients with inflammatory bowel disease 10.1111/imj.16141  

Smells like a variant: How the association between COVID-19 and olfactory dysfunction changed between 2019 and 2022 10.1111/joim.13760

Sodium-glucose cotransporter 2 inhibitors and nephrolithiasis risk in patients with type 2 diabetes 10.1001/jamainternmed.2023.7660

Suspected sepsis: recognition, diagnosis and early management (updated NICE guideline NG51)

Vitamin B12 deficiency in over 16s: diagnosis and management (new NICE guideline NG239)

Whipple's disease: A rare disease that can be spotted by many doctors 10.1016/j.ejim.2023.12.009


Cochrane Library (Mar); European Journal of Internal Medicine (Mar); Internal Medicine Journal (Mar); JAMA Internal Medicine (Mar); Journal of Community Hospital Internal Medicine Perspectives (Jan); Journal of Internal Medicine (Apr); NICE website (Mar)

February 2024

11β-Hydroxysteroid dehydrogenase and the brain: Not (yet) lost in translation 10.1111/joim.13741 

Audiovisual gamma stimulation for the treatment of neurodegeneration 10.1111/joim.13755 

The current best drug treatment for hypertensive heart failure with preserved ejection fraction 10.1016/j.ejim.2023.10.008

Diagnostic errors in hospitalized adults who died or were transferred to intensive care 10.1001/jamainternmed.2023.7347

Early and locally advanced breast cancer (updated NICE guideline NG101)

Efficacy and safety of prophylactic anticoagulation in patients with primary nephrotic syndrome 10.1111/imj.16227 

Evaluation of oseltamivir used to prevent hospitalization in outpatients with influenza 10.1001/jamainternmed.2023.0699

Health disinformation use case highlighting the urgent need for artificial intelligence vigilance: weapons of mass disinformation 10.1001/jamainternmed.2023.5947

Impact of antimicrobial stewardship in organisms causing nosocomial infection among COVID-19 critically ill adults 10.1016/j.ejim.2023.08.009

Intravenous iron: an update 10.1111/imj.16184 

The lingering symptoms of post-COVID-19 condition (long-COVID)  10.1111/imj.16251 

The Long-COVID autonomic syndrome in hospitalized patients 10.1016/j.ejim.2023.08.018

Long-term glucocorticoids in relation to the metabolic syndrome and cardiovascular disease 10.1111/joim.13739 

One-year outcomes following a hypertensive urgency or emergency 10.1016/j.ejim.2023.10.020

Optoelectronic control of cardiac rhythm: Toward shock-free ambulatory cardioversion of atrial fibrillation 10.1111/joim.13744 

Pathogenesis and management of immune dysfunction secondary to B cell haematological malignancies 10.1111/imj.16279 

Residual cardiovascular risk: When should we treat it? 10.1016/j.ejim.2023.10.013

The role of adherence in patients with chronic diseases 10.1016/j.ejim.2023.07.008

Suspected sepsis: recognition, diagnosis and early management (updated NICE guideline NG51)

Targeting the FGF19–FGFR4 pathway for cholestatic, metabolic, and cancerous diseases 10.1111/joim.13767 

Thrombo-inflammatory response in hospitalised patients with COVID-19 10.1111/imj.16285 

Tracheobronchial stents: an expanding prospect 10.1111/imj.16304 

Tuberculosis (updated NICE guideline NG33)

Sources used: European Journal of Internal Medicine (Jan-Feb); Internal Medicine Journal (Jan-Feb); JAMA Internal Medicine (Jan-Feb); Journal of Internal Medicine (Jan-Mar); NICE website (Jan-Feb)