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HSC Medicine, Dentistry and Healthcare Sciences Current Awareness Bulletins: Healthcare Science

Healthcare Science current awareness bulletin

Frequency: Bi-monthly

Links to articles in the current and previous 2 issues of this bulletin are displayed below.

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October 2025

Active phytoconstituents to tackle the resistance mechanism of MDR and XDR bacteria: a critical review

Antibiotic resistance of biofilm-forming bacteria causing urinary tract infections: a systematic review

Beyond genotype: challenges in predicting disease risk for carriers of biallelic perforin variants

A brain-derived tau oligomer polymorph is associated with cognitive resilience to Alzheimer's disease

Changes in early respiratory tract microecology associated with neonatal respiratory distress syndrome

CLIA immunoassay as an alternative and accurate method to detect SARS-CoV-2 antigen compared to ELISA

Clinical validation of a circulating tumor DNA–based blood test to screen for colorectal cancer

Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures

Dad's legacy: epigenetic reprogramming and paternal inflammatory memory in offspring health

Elevated toxic element emissions from popular disposable e-cigarettes: sources, life cycle, and health risks

Evidence gap in blood biomarkers for Alzheimer’s disease

Forensic pathology (NEJM review)

“Forever chemicals” - cutaneous exposure to per- and polyfluoroalkyl substances (PFAS): cause for concern?

HERV-W ENV transcription in B cells predicting symptomatic COVID-19 and risk for long COVID can express a full-length protein despite stop codon in mRNA from chromosome X via a ribosome readthrough

Metabolomics biomarkers for breast cancer: an updated perspective

Molecular sequence comparison for genome and S protein of COVID-19 virus from different countries

Molecular study of TNF-α, IL-1B and IL-10 genes in Eris Covid-19 patients

Molecular testing and targeted therapies in hepatobiliary cancers: a review

Pathogenesis of paroxysmal nocturnal hemoglobinuria

PI3Kγ in leukemia: class IB PI3 kinase reemerges as a cancer-intrinsic target

Plasma proteomic profiles predict individual future osteoarthritis risk

Possible Long COVID biomarker: identification of SARC-CoV-2 related protein(s) in serum extracellular vesicles

The role of crosstalk between NETs and keratinocytes in skin immunity

SARS-CoV-2 spike protein mutation variants: recent advances in theragnostic and vaccines development

Sex as a biological variable: a contemporary perspective

Sex differences in tissue-specific immunity and immunology

The spectrum of fragile X disorders

TMPRSS2 rs2070788 and rs383510 polymorphisms and laboratory markers as predictors for severity and mortality among COVID-19 patients: a single center study

Tumor molecular signatures: bridging the bench and the operating room

Vesicular monoamine transport inhibitors: current uses and future directions

Sources

ACS Central Science (Jun); Alzheimer’s & Dementia: the Journal of the Alzheimer’s Association (Aug); American Heart Journal (Sep); American Journal of Surgery, The (Aug); Arthritis & Rheumatology (Aug); Blood (Jun); BMJ, The (Aug); Cell (Jul); Clinical Breast Cancer (Aug); Diagnostic Microbiology and Infectious Disease (Aug); Infection (Jul); JAMA (Jun); JAMA Surgery (May); Journal of Internal Medicine (Jul); Journal of Investigative Dermatology (Aug); Microbes and Infection (Jul-Aug); Microbes and Infectious Diseases (Aug); NEJM (Jul-Aug); Science (Aug)

August 2025

Advancements and challenges in biomarker testing for tumors of the luminal gastrointestinal tract: current practice guidelines and emerging markers

A beginners guide to SELEX and DNA aptamers

Beyond the mucosa: unveiling selected mesenchymal lesions of the gastrointestinal tract

Biallelic SH2B3 germline variants are associated with a neonatal myeloproliferative disease and multisystemic involvement

Biological effects of pathologies in Lewy body diseases: why timing matters

A comprehensive review of computational methods for Protein-DNA binding site prediction

Decoding liver biopsies: a pattern-based approach

Endothelial dysfunction in patients with type 2 diabetes: the truth is in the blood

Gallbladder pathology: unveiling the latest breakthroughs

Histologic evaluation of gastrointestinal biopsies from immunocompromised patients

Induction of tunnelling nanotube-like structures by influenza A viruses requires the onset of apoptosis

Low‐complexity manual nucleic acid amplification tests for pulmonary tuberculosis in children (new Cochrane diagnostic review)

Novel proteins to neutralize venom toxins

Parallel use of low‐complexity automated nucleic acid amplification tests and lateral flow urine lipoarabinomannan assays to detect tuberculosis disease in adults and adolescents living with HIV (new Cochrane diagnostic review)

Parallel use of low‐complexity automated nucleic acid amplification tests on respiratory and stool samples with or without lateral flow lipoarabinomannan assays to detect pulmonary tuberculosis disease in children (new Cochrane diagnostic review)

Patient-specific in vivo gene editing to treat a rare genetic disease

Peripheral venous blood gas analysis for the diagnosis of respiratory failure, hypercarbia and metabolic disturbance in adults (new Cochrane diagnostic review)

Recent advances and challenges in graphene-based electrochemical biosensors for food safety

Selected laboratory‐based biomarkers for assessing vitamin A deficiency in at‐risk individuals (new Cochrane diagnostic review)

Sources

Analytical Biochemistry (Aug); Cochrane Library (May-Jun); Diagnostic Histopathology (Jun); European Journal of Human Genetics (Jun); Journal of Clinical Investigation, The (May); Lancet Neurology, The (May); NEJM (May-Jun); PLOS Pathogens (Jun)

June 2025

Academic training pathways in histopathology: practical perspectives

Advances in biosensors: a breakthrough in rapid and precise brucellosis detection

Animal models informing the role of the microbiome and its metabolites in rheumatoid arthritis

Artificial intelligence in haematopathology: current perspective and future directions

Developing AI-powered tools for histopathology: opportunities, challenges and new friends along the way

Diagnostic platforms for snakebite: current approaches and challenges in medically important species

Electrochemical flow injection analysis platforms for biomedical applications – progress and prospects

Entering the era of spatial transcriptomics: opportunities and challenges for pathology

Exploring the diagnostic landscape: portable aptasensors in point-of-care testing

Glycosyltransferase enzymatic assays: overview and comparative analysis

Head and neck mucosal manifestations of microbial infection: clinical presentation, histological features and diagnostic aids

Head and neck tumours with neuroendocrine marker ‘expression’: pitfalls and learning points

Identification and validation of programmed cell death related biomarkers for the treatment and prevention COVID-19

Integrating histopathology and epidemiology to explore cancer aetiology and survival

Macroscopy of oral and maxillofacial specimens

Nanopores for DNA and biomolecule analysis: diagnostic, genomic insights, applications in energy conversion and catalysis

Next-generation electrochemical biosensors for acrylamide: progress, challenges, and opportunities

An overview of biosensor advancements for detecting botulinum neurotoxins: addressing food safety and biowarfare risks

Quantification of amyloid-β aggregation inhibitors gallic acid and rosmarinic acid in biological samples by LC-MS/MS

Recent advancements in aptamers as promising nanotool for therapeutic and diagnostic applications

Spindle cell mesenchymal tumours of the head and neck: emerging and recently described entities characterised by molecular findings

Technical approaches for breath aldehyde biomarker detection and disease diagnosis: a review

Total flavonoid content revised: an overview of past, present, and future determinations in phytochemical analysis

Update on the dataset for histopathological reporting of salivary gland carcinomas: current concepts and controversies in salivary gland pathology

Sources

Analytical Biochemistry (May-Jul); Annals of Medicine (Apr); Diagnostic Histopathology (Apr-May); Rheumatic Disease Clinics of North America (May)

Disclaimer

The Healthcare Library cannot guarantee the correctness or completeness of the information in these bulletins. The information is subject to change and we cannot guarantee it will remain up-to-date. It is your responsibility to check the accuracy and validity of the information. These bulletins are the property of the Healthcare Library; please credit us if re-using or distributing content from them.